Mississippi Pot Roast is a Southern classic known for its rich, tangy, and buttery flavor.
Cooking it in an Instant Pot takes this dish to the next level—cutting down the cooking time while keeping the beef melt-in-your-mouth tender.
In this guide, you’ll learn everything about making Instant Pot Mississippi Pot Roast, including step-by-step instructions, expert tips, and FAQs to help you get perfect results every time.

Table of Contents
What is Instant Pot Mississippi Pot Roast?
The Origin of Mississippi Pot Roast
Mississippi Pot Roast originated from Robin Chapman, a home cook from Mississippi who wanted to make a less spicy version of her aunt’s pot roast. She simplified it using a ranch seasoning packet, au jus gravy mix, pepperoncini peppers, and butter.
It quickly became a household favorite, thanks to its tangy, buttery, and melt-in-your-mouth texture.
Why Use an Instant Pot Instead of a Slow Cooker?
While slow cooking takes 8+ hours, using an Instant Pot:
✔️ Cooks 70% faster
✔️ Locks in flavors with pressure cooking
✔️ Produces juicy, fork-tender beef
Looking for another Instant Pot beef dish? Try this flavorful Instant Pot Chuck Roast recipe that delivers juicy, tender meat every time!
Ingredients for the Best Mississippi Pot Roast
Essential Ingredients
To make a classic Instant Pot Mississippi Pot Roast, you’ll need:
- Chuck roast (3-4 lbs.) – The best cut for tenderness
- 1 packet Ranch seasoning mix – Adds herby tang
- 1 packet Au jus gravy mix – Deepens umami flavor
- 6-8 pepperoncini peppers – Brings a mild zesty heat
- 4 tbsp unsalted butter – Adds richness
- ½ cup beef broth – Helps with pressure cooking
Optional Ingredients for More Flavor
- 2 cloves garlic (minced) – Enhances depth
- 1 tbsp Worcestershire sauce – Boosts umami
- 1 tbsp brown sugar – Balances tanginess
- 1 tbsp Dijon mustard – Adds subtle spice
How to Cook Instant Pot Mississippi Pot Roast (Step-by-Step Guide)
Step 1: Sear the Chuck Roast

- Turn the Instant Pot to Sauté mode.
- Add 1 tbsp olive oil and brown the roast for 3-4 minutes per side.
- Remove and set aside.
Step 2: Add Liquid and Seasoning

- Pour ½ cup beef broth into the Instant Pot.
- Sprinkle the ranch seasoning and au jus mix over the roast.
- Add butter and pepperoncini peppers on top.
Step 3: Pressure Cook
- Lock the Instant Pot lid and set to high pressure for 60 minutes.
- Let the pressure naturally release for 15 minutes before opening.
Step 4: Shred and Serve

- Remove roast, shred with forks, and mix into the juices.
Pro Tip: Letting the roast sit for 5 minutes before shredding helps absorb juices better.
Cooking Time Adjustments Based on Meat Size
Roast Size | Pressure Cook Time | Natural Release |
---|---|---|
2 lbs | 50 minutes | 15 minutes |
3-4 lbs | 60 minutes | 15 minutes |
5+ lbs | 90 minutes | 15 minutes |
Can You Overcook Mississippi Pot Roast in an Instant Pot?
Unlike slow cooking, pressure cooking won’t dry out the meat but can make it too soft.
How to Prevent Overcooking
✔️ Use Natural Release for tenderness.
✔️ Avoid exceeding 120 minutes of cooking time.
Does the Roast Need to Be Covered in Liquid?
No! You only need ½ cup broth. Too much liquid makes the sauce too thin.
What to Serve with Instant Pot Mississippi Pot Roast
Classic Pairings
✔️ Mashed potatoes
✔️ Buttered egg noodles
✔️ Rice
Low-Carb Options
✔️ Cauliflower mash
✔️ Zucchini noodles
✔️ Steamed vegetables
How to Store & Reheat Leftovers
Storage Method | How Long It Lasts | Reheating Instructions |
---|---|---|
Refrigerator | 4 days | Microwave or stovetop with broth |
Freezer | 3 months | Thaw overnight, reheat in Instant Pot |
FAQ about Instant Pot Mississippi Pot Roast
How do you cook a Mississippi pot roast in the Instant Pot?
Follow these steps:
Sear the beef for flavor.
Add broth, seasoning, butter, and peppers.
Pressure cook for 60 minutes (3-4 lbs).
Natural release for 15 minutes.
Shred and serve!
Can you overcook Mississippi pot roast?
Yes, but overcooking doesn’t dry it out—it turns mushy instead.
Does roast need to be covered in liquid?
No, ½ cup of broth is enough for pressure cooking.